# RCSB_EXDB HISTORY
18-Mar-2019 V0.10 Initial version
22-Apr-2019 V0.11 Refining API, separate mock tests fro full cache tests, add taxonomy coverage accessors
23-Apr-2019 V0.12 Consolidated rcsb.exdb.seq into this more general module  (IN PROGRESS)
25-Jun-2019 V0.13 Update development workflows and cleanup
28-Jun-2019 V0.14 Migrating code from py-rcsb_utils_anal module for entity instance extraction
 4-Sep-2019 V0.15 Added tree, chemical reference loader operations and pipeline build tooling
17-Sep-2019 V0.16 Update to latest schemas
30-Sep-2019 V0.17 Updates for chemical reference and tree cli's and update dependencies
15-Oct-2019 V0.18 Refactor, add TaxonomyExtractor(), ReferenceSequenceAssignmentUpdater() and friends.
16-Oct-2019 V0.19 Checkpoint in improving update reference sequences and troubleshooting tree node lists for ATC
17-Oct-2019 V0.20 Checkpoint in refactoring reference sequence update processing.
18-Oct-2019 V0.21 Test version of document-level update of reference sequence assignments
18-Oct-2019 V0.22 Update cache file management
18-Oct-2019 V0.23 Adjust filter behavior, turn off test mode, fix Py27 test parameter.
19-Oct-2019 V0.24 Handle miscellaneous issues in reference sequence processing from Oct 18 full load
20-Oct-2019 V0.25 Handle duplicates from inconsistent struct_ref_* records
 5-Dec-2019 V0.26 Add support for entity typed schema and update dependencies.
 6-Dec-2019 V0.27 Add match index cache recovery.1
11-Dec-2019 V0.28 Adding reference sequence loader and moving pipeline to py38.
15-Dec-2019 V0.29 Added methods to load UniProt features
17-Dec-2019 V0.30 Pre-filter GOIDs and add ExDbWorkflow module with simple wf entry points
20-Dec-2019 V0.31 Adjust package definition
23-Dec-2019 V0.32 Change protocol for supplementing accessions and EC annotations.
04-Jan-2020 V0.33 Add support for rcsb_polymer_entity.rcsb_enzyme_class_combined_depth
09-Jan-2020 V0.34 Add additional cache test criteria for UniProt match cache.
10-Jan-2020 V0.35 Update dependencies for rcsb.utils.go and rcsb.utils.struct
23-Jan-2020 V0.36 Changes to support pre-beta-v1 schema reorganization with the addition of rcsb_polymer_entity_annotation
27-Jan-2020 V0.37 Add annotation extractor modules and adjustments for some missing features.
29-Jan-2020 V0.38 Update dependencies for GO and Drugbank fixes
30-Jan-2020 V0.39 Update dependencies structure domain utilities
 2-Feb-2020 V0.40 Add test fixtures to measure memory usage, streamline some extractions, suppress some diagnostic reporting
 4-Feb-2020 V0.41 Update dependencies to support split configuration
 6-Feb-2020 V0.42 Address issue with duplicated annotations from multiple reference sequences
 8-Feb-2020 V0.43 Adjust the default chunk size in the workflow interface (set the default to 100)
 8-Feb-2020 V0.44 Expose the reference sequence fetch chunk size in the workflow interface
11-Feb-2020 V0.45 Simplify workflow api and update dependencies
13-Feb-2020 V0.46 Added validation tests to troubleshoot UniProt core loading.  Update dependencies.
16-Feb-2020 V0.47 Add alternative cache strategy for reference sequences.
19-Feb-2020 V0.48 Add Pfam and InterPro Providers and associated annotation
20-Feb-2020 V0.49 Combine missing UniProt accessions if available with other reference sequence data.
26-Feb-2020 V0.50 Standardize case for gene names.
 1-Apr-2020 V0.51 Better handling of incomplete primary gene annotations
