{% extends "base.html" %} {% block head %} {{ super() }} {% endblock %} {% block title %}{{ graph }}{% endblock %} {% block content %}
{% if graph.description %} {{ graph.description }} {% else %} Provenance information is extracted from the header in the source BEL document. {% endif %}
Each node in a BEL graph is assigned a type. Most nodes are then identified with a namespace:identifier pair, or a definition based on other nodes as in the case of complexes, composites, and chemical reactions.
| Reference | BEL |
|---|---|
| {{ d['citation'].curie }} | {{ graph.edge_to_bel(u, v, d) }} |
These pairs of nodes represent motifs like A increases B and
B decreases A.
| Node A | Node B |
|---|---|
| {{ source }} | {{ target }} |
These pairs of nodes have a contradiction in their causal relationships, meaning they
have more than one of INCREASES, DECREASES, or CAUSES NO
CHANGE. This may be due to different experimental conditions, so these statements
need to be carefully considered in analyses.
| Source | Relations | Target |
|---|---|---|
| {{ source }} | {{ ', '.join(relations) }} | {{ target }} |
A increases
B and B increases A.
A decreases
B and B decreases A.
While neither chaotic nor dampened pairs are biologically invalid, they require additional context to understand their regulation.
| Type | Node A | Node B |
|---|---|---|
| {{ label }} | {{ source }} | {{ target }} |
Analysis of triple stability comes from a deep graph theoretic background. It identifies triangles within the graph that have logically inconsistent relations.
A positiveCorrelation B, B negativeCorrelation
C, but C positiveCorrelation A.
A negativeCorrelation B, B negativeCorrelation
C, and C negativeCorrelation A.
A increases B, A decreases C, and C
positiveCorrelation A.
A increases B, A increases C, and C
negativeCorrelation A.
A decreases B, A decreases C, and C
negativeCorrelation A.
| Type | Node A | Node B | Node C |
|---|---|---|---|
| {{ label }} | {{ a }} | {{ b }} | {{ c }} |
Like unstable pairs, unstable triplets require additional context to understand their mechanisms of regulation.
A
increases B, B increases C, and C increases A.
A
decreases B, B decreases C, and C decreases A.
| Type | Node A | Node B | Node C |
|---|---|---|---|
| {{ label }} | {{ a }} | {{ b }} | {{ c }} |
Pathologies are more dogmatically the result of molecular and physical processes, and do not necessarily make sense as the subject of causal statements.
| Source | Relation | Target |
|---|---|---|
| {{ source }} | {{ relation }} | {{ target }} |