Metadata-Version: 2.4
Name: DILImap
Version: 1.0.2
Author-email: Volker Bergen <vbergen@cellarity.com>
License-File: LICENSE
Classifier: License :: Other/Proprietary License
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Description-Content-Type: text/x-rst

DILImap & ToxPredictor
======================

**DILImap** is a pioneering toxicogenomics atlas purpose-built for modeling Drug-Induced Liver Injury (DILI).
It features RNA-seq profiles from primary human hepatocytes exposed to 300 diverse compounds. It offers a powerful foundation for mechanistic insight and predictive modeling.

**ToxPredictor**, trained on DILImap, sets a new benchmark in DILI risk assessment. With 89% sensitivity at 100% specificity,
it outperforms traditional methods and reliably flags even the most elusive DILI-prone drugs, including withdrawn and idiosyncratic compounds.

.. image:: https://github.com/user-attachments/assets/bbe2af70-c8ee-4fe1-8448-0858b9d1dd09
   :width: 724
   :alt: image

Usage & Support
---------------

- **Installation**: Install using :code:`pip install dilimap`

- **Documentation & Notebooks**: Visit `dilimap.org <https://dilimap.org/>`_ for detailed usage instructions and reproducibility notebooks.
  *(Note: Access is restricted — see manuscript for the tokenized link.)*

- **Support**: Reach out at `DILImap@cellarity.com <mailto:DILImap@cellarity.com>`_ with any questions or feedback.


.. |actions| image:: https://github.com/Cellarity/dilimap/actions/workflows/ci.yaml/badge.svg?branch=main
   :target: https://github.com/Cellarity/dilimap/actions/workflows/ci.yaml
   :alt: Continuous Integration Status: GitHub actions

.. |rtd| image:: https://readthedocs.com/projects/vl49-dilimap/badge/?version=latest&token=41c19a846e0be9f882d76528ec32ac7358d7234fd0cf158051bf81965d7d5359
   :target: https://docs.cellarity.com/dilimap/en/latest/?badge=latest
   :alt: Documentation Status
