kappa = 2.38822
omega = 0.281251
phi0A = 0.255391
phi0C = 0.257621
phi0G = 0.360967
phi1A = 0.274267
phi1C = 0.242454
phi1G = 0.212275
phi2A = 0.200391
phi2C = 0.28751
phi2G = 0.298419